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GLP-1 medications work by targeting multiple systems in the body to support weight loss and improve metabolic health. Here’s a breakdown of their mechanisms:

Appetite Suppression: GLP-1 agonists act on receptors in the brain to reduce hunger and increase feelings of fullness. This helps you consume fewer calories without feeling deprived.
Slowed Gastric Emptying: These medications slow the rate at which food leaves the stomach, helping you feel satisfied longer after meals and reducing post-meal blood sugar spikes.
Improved Insulin Sensitivity: GLP-1 agonists stimulate the pancreas to release insulin in response to meals, improving blood sugar control. They also suppress glucagon, a hormone that raises blood sugar levels.
Enhanced Metabolism: By supporting glucose metabolism and reducing cravings, GLP-1 medications help your body burn energy more efficiently.
For example, in clinical trials, Semaglutide (Wegovy) led to an average weight loss of 15% of body weight, while Tirzepatide (Zepbound) achieved up to 20% weight loss when paired with diet and exercise. These results far surpass traditional diet and exercise alone, which typically yield 2-3% weight loss.

At ShedRx, we combine GLP-1 medications with personalized coaching and supplements like Shed GLP-1 Revive and Shed Protein to maximize your results. Our approach ensures you’re not just losing weight but building sustainable habits to maintain it.